Conn's Syndrome

Original article by Tom Leach | Last updated on 22/11/2013
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Conn’s Syndrome
This is basically primary hyperaldosteronism. It will cause hypernatreamia and hypokalaemia.
It is a recognised cause of hypertensionbut it is rare. It can also cause alkylosis (due to the exchange of sodium for hydrogen by some channels in the tubule).
It is often symptomless, but may present with symptoms of hypokalaemiasuch as muscle weakness, fatigue, polyuria, cramps.
2/3 are due to a solitary mineralocorticoid producing adrenal adenoma. The other 1/3 are due to adrenal hyperplasia.
The treatment is basically laparoscopic adrenalectomy