Bullous Pemphigoid

Aetiology Elderly (>65yrs) Vaccinations (in children with  condition affecting face, palms and soles)  NSAIDs, furosemide, antibiotics UV radiation / x-rays   Pathophysiology Autoimmune, subepidermal blistering due to IgG  autoantibodies for the basement membrane proteins...

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Bullous Pemphigus

Aetiology  Middle aged (40-60yrs)  High prevalence in Jewish regions  Lifelong condition   Pathophysiology Autoimmune, epidermal blistering due to IgG  autoantibodies for keratinocyte surfaces (desmoglein) Often mucosal involvement (>90%) Potentially life threatening (rare) if it...

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