Pancreatic Cancer

Introduction Pancreatic cancers are 95% exocrine, adenocarcinomas. These affect the duct or surround the duct. The remaining 5% are neuroendocrine tumours e.g. insulinomas, glucagonomas (the former being the more common). This article pertains to...

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Pancreatitis

Introduction Pancreatitis is a condition involving inflammation of the pancreas. It can be acute or chronic; acute pancreatitis can return to normal after resolution of the episode, conversely chronic pancreatitis, is continuing inflammation, often with irreversible...

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Peptic Ulcer Disease

Summary Epidemiology More common in men than women DU’s and 2-3x as common as GU’s Aetiology H. pylori infection Smoking –reduces prostaglandin synthesis Alcohol intake NSAID use – reduced prostaglandin synthesis Pathology H. pylori produces...

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PR exam

Indications Change of Bowel habit – constipation, diarrhea, tenesmus Rectal bleeding Perianal symptoms e.g. pain/itching/discharge Urinary symptoms in men (for BPH) Assessment of anal tone in neurological exam            ...

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Primary Sclerosing Cholangitis

Introduction Primary Sclerosing Cholangitis (PSC) is a chronic inflammatory condition that results in the fibrosis and destruction of intra-hepatic and extrahepatic bile ducts. This can lead to cholestasis, hypertension and liver failure. Epidemiology 75%...

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Pyloric Stenosis

Epidemiology More common in boys (4:1) Often a maternal family history Increased risk if siblings were affected Erythromycin exposure in first few weeks of life Pathology There is a functional obstruction of the pyloric...

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