Autoantibodies

Quick summary of Autoantibodies   Antibody Disease Anti-dsDNA SLE Anti-mitochondrial Primary Biliary Sclerosis ASMA – Anti- smooth muscle antibody Chronic active hepatitis pANCA Ulcerative Colitis cANCA Wegner’s granulomatosis Anti-endomysial / gliadin / transglutamase Coeliac...

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Autoimmune Hepatitis

Introduction Autoimmune hepatitis (AIH) is a cause of chronic hepatitis. It is also sometimes referred to as chronic active hepatitis.  Any hepatitis that typically lasts >6 months is referred to as chronic. It is characterised by: Increased IgG...

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Autosomal Dominant Polycystic Kidney Disease (ADPKD)

ADPKD is an autosomal dominant disorder characterised by the presence of cysts in both kidneys. The cysts are numerous and fluid-filled, resulting in massive enlargement of the kidneys, often with progression to renal failure. The disease...

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