Macrocytic Anaemias

Introduction Anaemia is one of the most common presenting complaints to general practice. One of several ways in which anaemias can be classified, is by red cell size. As such, anaemias can be said...

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Macular Degeneration

Introduction Macular degeneration (aka age-related maculopathy – ARM) is a condition that causes gradual visual loss, typically in older patients. It can be split into two types: Dry – atrophic Wet – exudative Red flags for...

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Malaria

Introduction Presentation can be vague, any or all of wide variety of symptoms. Always should be considered in unwell patients returning from or having passed though endemic areas Organism Parasite is a plasmodium (protozoan)....

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Malignant Hypertension

Introduction Malignant hypertension (aka – hypertensive crisis) is a very high blood pressure that typically comes on suddenly and quickly. It is defined as systolic blood pressure of >180 mmHg and / or diastolic blood pressure...

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Marfan Syndrome

Introduction Marfan Syndrome (sometime Marfan’s Syndrome) is an autosomal dominant connective tissue disorder. Epidemiology and Aeitiology 25% of cases occur without family history Reduced life expectancy – average is around 60 Pathology The result...

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Measles

Introduction Now relatively rare in the UK Older children have more severe disease Caused by the Morbillivirus, which is a type of paramyoxovirus This is a single stranded, enveloped RNA virus It is a...

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Mechanical Back Pain

Introduction Mechanical back pain (aka non-specific back pack, sometimes previously termed lumbago) is a term used to describe musculoskeletal lower back pain. It is extremely common, with about 80% of those in Western Society...

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Medication Overuse Headache

Introduction Medication overuse headache (AKA rebound headache) usually occurs in patients with a past medical history of severe headache, for which they have frequently/ excessively used analgesics. Clinical Features Chronic headache occurring >15 days...

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Memantine

Memantine is an N-methyl-D-aspartate (NMDA) antagonist and is licensed for use in moderate-severe Alzheimer’s disease (AD). Mechanism of Action Memantine is an NMDA antagonist (AKA Glutamate receptor antagonist) NMDA receptor found on post synaptic...

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