Myasthenia Gravis

Introduction Myasthenia Gravis is an acquired, autoimmune condition. Antibodies attack the Acetylcholine receptor. This gives weakness in muscles, particularly the ocular, bulbar and proximal skeletal. Fatigability is a key symptom! Disease has a fluctuating...

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Mycoplasma Pneumonia

Introduction Mycoplasma pneumoniae is a small bacterium (one of the the smallest free-living organisms), that lacks a cell wall, which can cause a pneumonia in humans – termed mycoplasma pneumonia Along with some other organisms...

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Myelofibrosis

Marrow fibrosis and splenomegaly, de novo or following transformation of PV or ET Usually >50 years old Abnormal megkaryocytes produced in increased numbers. PDGF and TGFβ are released by megakaryocytes, stimulating fibrosis. Haematopoietic stem...

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Myeloma

Introduction Myeloma is a malignant disease of the plasma cells of the bone marrow.  Its name suggests that it is a disease of the myeloid stem cells, but this is not the case. All blood...

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Myeloproliferative Diseases

Clonal proliferation of haematopoietic components in the bone marrow leads to an increase in numbers of one or more lineages of mature blood cells. Myeloproliferative disorders have the potential to transform into acute leukaemia.

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Myocarditis

What is Myocarditis? Myocarditis is an inflammation of the myocardial layer of heart muscle. Myo=muscle, card=heart, itis=inflammation. The heart wall is made of 3 layers: Endocardium(layer of endothelium & connective tissue lining the inside...

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