Renal Physiology

Introduction Cortical nephrons make up 85% of nephrons. Juxtamedullary nephrons make up 15% of nephrons. There is a visceral epithelium that covers the glomerular capillaries inside Bowmann’s capsule. This is just one cell thick,...

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Renal Replacement Therapy

Introduction The different types of renal replacement therapies include haemodialysis, peritoneal dialysis, haemofiltration, and renal transplation. Haemodialysis (HD) This can be carried out on an outpatient or an inpatient basis. In the context of this explanation it is...

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Renal Stones

Introduction Renal stones are precipitates that form from urine due to a high concentration of that particular precipitate in the urine. The most common (85%) precipitate is calcium;  particularly calcium oxalate, about 10% are...

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Renin Inhibitors

  Mechanism of action Renin Inhibitors act by > directly inhibit renin! Renin converts angiotensinogen to angiotensin I Renin inhibitors (Aliskiren) competes with angiotensinogen for the active site of the renin enzyme Reduces plasm...

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