Transplant Reactions

Hyperacute Rejection Occurs within minutes (to hours) – so quick that the surgeon is sometimes able to visualise characteristic changes whilst sill performing the anastomosis of blood vessels. There is rapid agglutination (clumping together...

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Trauma

Introduction Trauma is managed by teams in the Emergency Department. There is often a defined set of individuals on a ‘Trauma Team’. This might include: Team Leader – often an Emergency Physician / Registrar...

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Trichomoniasis

Introduction This is a parasitic protozoan infection, the result of infection with the flagellated anaerobic trichomonas vaginalis. This is the most common protozoan infection in the developed world It is a sexually transmitted infection...

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Tricyclic Antidepressants

Introduction Tricyclic Antidepressants e.g. Amitriptyline, imipramine, lofepramine There are also related compounds, that are not technically tricyclics, but that we will consider as the same here: amoxapine, maprotiline Mechanism They inhibit the uptake of monoamines...

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Tricyclic Overdose

Introduction Tricyclic Medications (sometimes called tricyclic antidepressants, or TCAs) for example;  amitriptyline, dosulepin, are commonly taken in overdose. They are probably one of the more dangerous medications to use in overdose, and can be...

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