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		<title>Contraception &#8211; Combined Oral Contraceptive Pill &#8211; COCP</title>
		<link>https://almostadoctor.co.uk/encyclopedia/pills-and-similar-preparations</link>
					<comments>https://almostadoctor.co.uk/encyclopedia/pills-and-similar-preparations#respond</comments>
		
		<dc:creator><![CDATA[Dr Tom Leach]]></dc:creator>
		<pubDate>Wed, 14 Jun 2017 14:57:19 +0000</pubDate>
				<category><![CDATA[Obstetrics and Gynaecology]]></category>
		<category><![CDATA[Sexual Health]]></category>
		<category><![CDATA[Contraception]]></category>
		<guid isPermaLink="false">http://almostadoctor.co.uk/?post_type=encyclopedia&#038;p=1474</guid>

					<description><![CDATA[<p>Introduction Combined oral contraceptive pills contain both oestrogen and progestogen. This method is: Reliable and reversible Can reduce dysmennorrhoae (painful menstruation) and menoorhagia (heavy bleeding) Can reduce PMT (pre-menstrual tension) Reduce the risk of ovarian, endometrial and colon cancer Reduce the risk of PID An effective treatment for acne and endometriosis Reduce risk of fibroids and ovarian cysts [&#8230;]</p>
<p>The post <a href="https://almostadoctor.co.uk/encyclopedia/pills-and-similar-preparations">Contraception &#8211; Combined Oral Contraceptive Pill &#8211; COCP</a> appeared first on <a href="https://almostadoctor.co.uk">almostadoctor</a>.</p>
]]></description>
										<content:encoded><![CDATA[<h3><b>Introduction</b></h3>
<div>Combined oral contraceptive pills contain both oestrogen and progestogen. This method is:</div>
<ul>
<li>Reliable and reversible</li>
<li>Can reduce dysmennorrhoae (painful menstruation) and menoorhagia (heavy bleeding)</li>
<li>Can reduce PMT (pre-menstrual tension)</li>
<li><b>Reduce</b> the risk of ovarian, endometrial and <a class="ilgen" href="/encyclopedia/colorectal-cancer">colon cancer</a></li>
<li>Reduce the risk of PID</li>
<li>An effective treatment for <a class="ilgen" href="/encyclopedia/acne-vulgaris">acne</a> and <a href="https://almostadoctor.co.uk/encyclopedia/endometritis">endometriosis</a></li>
<li>Reduce risk of <a class="ilgen" href="/encyclopedia/fibroids">fibroids</a> and ovarian cysts</li>
</ul>
<div>The COCP pill is frequently prescribed, but, from the prescribers perspective is also one of the more complex methods of contraception due to the long list of contraindications and cautions.</div>
<div></div>
<div>COCP preparations can be divided into three main types:</div>
<p><b><i>Monophasic – </i></b>each pill contains the same amount of progesterone and oestrogen.<br />
<b><i>Phasic –</i></b> the concentrations of hormones in each pill varies with the time of the cycle.</p>
<ul>
<li><i><span style="color: red;">Both monophasic and phasic pills are in a 21 day supply, </span>with a 7 day break from days to allow breakthrough bleeding. <b><span style="color: #0070c0;">Patients are still protected from <a class="ilgen" href="/encyclopedia/normal-physiology-of-pregnancy">pregnancy</a> during the 7 day period, </span></b><span style="color: #0070c0;">provided all the other pills were taken correctly.</span></i></li>
</ul>
<p><b><i>Every Day pills – </i></b><i>28 days supply, with 7 days of placebo pills in days 22-28. <b>The pills must be taken in the right order. </b></i></p>
<div>They are available in varying strengths. The lowest dose that produces the desired effects should be used. Typically the oestrogen component is a variant of oestrogen known as <b><i>ethinylestradiaol </i></b>– and typically doses are 20 – 40 micrograms. COCPs may contain a variety of progestogens such as norethisterone, levonorgestrel or desogestrel.</div>
<ul>
<li>Note that it is perfectly safe to &#8220;run together&#8221; courses of the 21 days of active pills. This can be done for up to 12 months at a time if desired</li>
<li>Most women have breakthrough bleeding within 120 days of doing this</li>
<li>If this occurs, advise patients to stop the pills for 7 days to allow for a withdrawal bleed before recommencing</li>
</ul>
<blockquote><p>Prescribing the COCP is not a simple process of &#8220;just writing the prescription&#8221; although patients may feel frustrated at repeated thorough risk fact-checking at the time of prescription. In my career I have upset many women by refusing to prescribe the pill when contraindicated &#8211; even when they have been previously taking it for a long time. I have also seen the death of a teenage girl from massive PE shortly after starting on the pill, and several other cases of PE and huge DVT. This is rare but it certainly comes to mind whenever I write a prescription! &#8211; <em>Dr Tom Leach</em></p></blockquote>
<h3><strong>Summary</strong></h3>
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<div><b><a class="ilgen" href="/encyclopedia/contraception">CONTRACEPTION</a></b></div>
</td>
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<div><b>COMBINED PILL</b></div>
</td>
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<div><b>EFFECTIVENESS</b></div>
</td>
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<div>&gt;99% when taken correctly.</div>
</td>
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<div><b>PREPERATIONS</b></div>
</td>
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<div>e.g. Microgynon (<i>Ethinylestradiol and levonorgestrel)</i></div>
</td>
</tr>
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<div><b>HOW IT WORKS</b></div>
</td>
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<div>Contains both oestrogen and progesterone.</div>
<div>Stops ovulation</div>
<div>Thickens cervical mucus preventing passage of perm, thins lining of uterus preventing implantation.</div>
</td>
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<div><b>ADVANTAGES</b></div>
</td>
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<div>Very effective when taken correctly</div>
<div>reduces bleeding, pain and PMT.</div>
<div>Reduced hirtuism and acne</div>
<div>Reduces risk endometrial and ovarian ca. Possibly [controversial] inc risk <a class="ilgen" href="/encyclopedia/breast-cancer">breast ca</a>.</div>
<div>Fertility quick to return when ceased, but can take up to 3 months</div>
</td>
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<div><b>DISADVANTAGES</b></div>
</td>
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<div><b>Progestrogens cause :</b><a class="ilgen" href="/encyclopedia/headache">Headache</a>, Breast tenderness, breakthrough bleeding</div>
<div><b>Oestrogens cause: </b>Nausea and vomiting, Fluid <a class="ilgen" href="/encyclopedia/urinary-retention">retention</a>, Mood changes</div>
<div>Inc risk of <a href="https://almostadoctor.co.uk/encyclopedia/atherosclerosis-and-coronary-heart-disease-chd">cardiovascular disease</a> (<b><i>thromboembolism</i></b>)</div>
</td>
</tr>
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<div><b>CI</b></div>
</td>
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<div><b><i>Absolute CI’s &#8211; </i></b><i>see <a href="https://www.fsrh.org/standards-and-guidance/documents/ukmec-2016-summary-sheets/">UKMEC</a> for a full list</i></div>
<div><a class="ilgen" href="/encyclopedia/migraine">Migraine</a> – with typical focal aura, or severe migraine &gt;72hrs,</div>
<div>Personal history venous or arterial thrombosis,</div>
<div>Heart disease</div>
<div>Previous <a class="ilgen" href="/encyclopedia/dvt-and-pe">DVT</a> or PE, <a class="ilgen" href="/encyclopedia/stroke">Stroke</a></div>
<div>FHx in first degree relative of VTE</div>
<div><a class="ilgen" href="/encyclopedia/liver-physiology">Liver</a> disease</div>
<div><a href="https://almostadoctor.co.uk/encyclopedia/diagnosis-pathology-and-management-of-hypertension">BP&gt;160/95</a></div>
<div>Age &gt;50, or age &gt;35 and smoker</div>
<div>Smoker &gt;40/day any age</div>
<div>Increased BMI &#8211; avoid if BMI &gt;35, caution if 30-35</div>
<div></div>
<div><b><i>Avoid if two or more of following:</i></b></div>
<div>Fx venous thromboembolism / arterial disease, obesity, long-term immobilization, <a class="ilgen" href="/encyclopedia/varicose-veins">varicose veins</a>.</div>
<div>DM, <a class="ilgen" href="/encyclopedia/diagnosis-pathology-and-management-of-hypertension">hypertension</a>, smoking, &gt;35yrs, obesity, migraine</div>
<div></div>
<div>NB: <a class="ilgen" href="/encyclopedia/epilepsy">epilepsy</a> (particularly carbamazepine) drugs and ST. john&#8217;s Wort interfere with COCP metabolism so patients on these drugs may need higher doses.</div>
</td>
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<div><b>COMMENTS</b></div>
</td>
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<div>Take 21 pills and one week off (some preparations have placebo 7 days, in a 28 day packet)</div>
<div>Start first course on 1<sup>st</sup> day period. If starting after day 4 of period, or if miss pill &gt;24hr time allocation must use barrier contraception for 7 days.</div>
</td>
</tr>
</tbody>
</table>
<h3><b>Efficacy</b></h3>
<ul>
<li>Quoted as &gt;<b><i><span style="color: #0070c0;">99% effective</span></i></b></li>
<li>Described as: if taken correctly, then during the course of 1 year, &lt;1% of women taking the COCP will become <a class="ilgen" href="/encyclopedia/dystocia">pregnant</a></li>
<li>With typical &#8216;real-world&#8217; use efficacy is more like 91%</li>
</ul>
<h3><b>Mechanism</b></h3>
<ul>
<li>Prevents ovulation by suppression of LH and FSH
<ul>
<li>LH and FSH levels should not be tested whilst on the pill as the result cannot be interpreted</li>
<li>It typically takes about 7 days of hormonal therapy to suppress ovarian function, and 7 days without the pill for it it start functioning again. However, it can take up to 3 months for fertility to return after ceasing the pill</li>
</ul>
</li>
<li>Thickens cervical mucous</li>
<li>Alters uterine lining to prevent implantation</li>
</ul>
<h3><b>Side effects</b></h3>
<p>Oestrogen increases the risk of cardiovascular disease (notably thromboembolus). It also causes:</p>
<ul>
<li><b><i><span style="color: #0070c0;">Nausea </span></i></b><i>(progesterone does not)</i></li>
</ul>
<p>Progestogens can cause: headache, <a class="ilgen" href="/encyclopedia/depression">depression</a>, acne, breakthrough bleeding and breast symptoms. <i><span style="color: red;">Many of these resolve themselves after several weeks/months of treatment, </span></i>and can be solved if a different progestrogen is used, however, some progestogens are also associated with increased thromboembolic risk</p>
<ul>
<li><b><span style="color: #0070c0;">Thromboembolic risk – </span></b>is increased in those taking the COCP, particularly during the first year of use, but the risk is small, and smaller than in pregnancy (when the risk is 60 per 100 000).</li>
<li><i><span style="color: #0070c0;">In all patients the risk of thromboembolism increases with age. </span></i></li>
<li>There is also an increased risk of DVT when travelling (&gt;5 hour flights) and women should be informed of and encouraged to perform inflight exercises.</li>
<li><b>Breakthrough bleeding </b>is particularly common in the first few months, but usually resolves.</li>
<li><b>The risk of weight gain </b>on the COC is unproven</li>
</ul>
<div></div>
<h3><b><i>Missed doses</i></b></h3>
<p>The general rule is that the combined pill <b><i>can be taken within 24 hours of the usual time of administration, and still be effective. </i></b><br />
If a pill is missed, the woman should take it as soon as she remembers, and then continue taking the rest of the pills at their normal time; even if this means taking two at once<br />
A ‘missed pill’ is one that is &gt;24 hours after she should have taken it</p>
<ul>
<li><span style="color: #0070c0;">Just missing one pill is not a problem, nor is starting a new pack one day late, </span><b><i>as long as the missed pill is taken with the next one. </i></b></li>
</ul>
<p>The greatest risk of pregnancy if a pill is missed is at the beginning and end of a cycle.<br />
<b><span style="color: red;">If 2 pills are missed </span></b><i>(i.e. &gt;24 after time should have been taken) </i><b><span style="color: red;">then there is a risk of pregnancy – </span></b>especially if the pill was missed in the first 7 days of the cycle.</p>
<ul>
<li>If the patient has had sexual contact during the missed period, <b><span style="color: #0070c0;"><a class="ilgen" href="/encyclopedia/emergency-contraception">emergency contraception</a> is recommended. </span></b></li>
<li>If not, then the advice is to continue taking the rest of the pills as normal, <b><i>and use an additional method of contraception </i></b><i>(e.g. condoms) <b>for 7 days. </b></i>If this 7 days includes the 7 days ‘break’ at the end of the cycle, the next packet should be started immediately, and the ‘break’ omitted.</li>
<li>The patient <b><i>should not take the missed pills if &gt;2 pills were missed. </i></b></li>
</ul>
<div></div>
<h4><b><i>Vomiting and diarrhoea</i></b></h4>
<ul>
<li>If vomiting occurs within 2 hours of taking a pill, another pill should be taken</li>
<li>If there is vomiting or <a class="ilgen" href="/encyclopedia/diarrhoea">diarrhoea</a> for &gt;24 hours, then this should be treated the same as a <b><i>missed pill – </i></b>i.e: the pills should be taken as normal, but additional contraception (e.g. condoms) should be used for 7 days after the end of the period of illness. If this 7 days runs into the last 7 days of the cycle, the next packet of pills should be started straight away, and the ‘break’ omitted.</li>
</ul>
<h4><b><i>Drug interactions</i></b></h4>
<div>Several drugs are known to reduce the effectiveness of the pill (<b><i>’enzyme inducing drugs’</i></b>). You should always check other medications the patient is on (in the BNF) before prescribing a contraceptive, and seek expert advice. Some common examples of interactions are given below:</div>
<ul>
<li><i><span style="color: #0070c0;">Carbamazepine</span></i></li>
<li><span style="color: #0070c0;">Pheytoin</span></li>
<li><span style="color: #0070c0;">Phenobarbital</span></li>
<li><b><span style="color: red;">St John’s Wort</span></b></li>
<li><b><span style="color: #0070c0;">Rifabutin</span></b></li>
<li><b><span style="color: #0070c0;">Rifampicin</span></b></li>
</ul>
<div>In women taking these drugs it is advisable to seek alternative methods of contraception</div>
<p><b><span style="color: red;">When taking a course of <a class="ilgen" href="/encyclopedia/antibiotics-drug-classes-and-mechanisms">antibiotics</a></span></b></p>
<ul>
<li>Somewhat controversial</li>
<li>Previous guidance advised this could affect pill efficacy</li>
<li>More recent evidence suggests that it probably doesn&#8217;t</li>
<li>Many s places still advise additional form of contraception:
<ul>
<li>e.g. use condoms during the course and for 7 days afterwards.</li>
<li><i>If you pass day 21 of the packet, then start a new packet immediately, even for <b>everyday pills. </b></i></li>
<li>If the course of AB’s lasts longer than 2 weeks, alternative methods of contraception should be sought</li>
</ul>
</li>
</ul>
<h4><b><i>Surgery</i></b></h4>
<div>It is advisable to discontinue all oestrogen-containing contraceptive 4 weeks before major surgery to reduce the thromboembolus risk. You can safely resume them at the first menses &gt; 2 weeks after surgery.</div>
<div></div>
<h3><b>Contraindications / reasons to stop taking immediately</b></h3>
<ul>
<li>BP &gt;160/95</li>
<li>Hepatitis, <a class="ilgen" href="/encyclopedia/bilirubin-metabolism-and-jaundice">jaundice</a>, <a class="ilgen" href="/encyclopedia/causes-of-hepatomegaly">hepatomegaly</a></li>
<li>Prolonged immobility (e.g. usually after surgery)</li>
<li>Sudden onset pain:
<ul>
<li>In chest (with/without radiation)</li>
<li>Headache</li>
<li>Stomach</li>
</ul>
</li>
<li>Sudden onset calf swelling</li>
<li>Sudden breathlessness</li>
<li><b><i>Migraine with aura, </i></b><i>or migraine lasting &gt;72 hours, or migraine resistant to treatment</i>
<ul>
<li>Increased risk of ischaemic stroke in these patients</li>
</ul>
</li>
<li><b>Age over 50</b></li>
<li><b>Smoker &gt;40/day</b></li>
<li><b><a class="ilgen" href="/encyclopedia/introduction-to-diabetes">Diabetes</a> with complications, </b>or diabetes &gt;20y</li>
<li><i><span style="color: red;">Breast feeding – </span></i>avoid during the first 6 months due to effects on lactation</li>
<li>BMI &gt;35, caution if BMI 30-35</li>
</ul>
<h4><b>Cautions</b></h4>
<div><i>If two or more of the following are present, alternative contraception should be recommended</i></div>
<ul>
<li>Age over 35</li>
<li><b>Obesity</b>
<ul>
<li>BMI &gt;30-35</li>
</ul>
</li>
<li>Migraine (without aura)</li>
<li>BP &gt;140/90</li>
<li>Smoker &lt;40/day</li>
<li>FHx of arterial disease</li>
<li>Diabetes &lt;20y</li>
</ul>
<h3><b>Prescribing</b></h3>
<p>Women with RF’s for cardiovascular disease should be prescribed the lowest does of oestrogen (20micrograms ethinylestradiol), or should be prescribed an alternative if &gt;2 RF’s are present<br />
Women &gt;50 should not use the COC as better alternatives are available, and the cardiovascular disease risk is high<br />
<i><span style="color: red;">Inform patient to seek help immediately if:</span></i></p>
<ul>
<li>Migraines, sudden onset chest pain/breathlessness/haemoptysis, swollen calves, weakness is limbs / other signs of TIA/stroke</li>
</ul>
<p><b>Missing the withdrawal bleed</b></p>
<ul>
<li>It is ok to use two packets one after the other (i.e. start the second packet on day 22). This can be done for up to 3 months in a row. Tell the patient the lining of the womb does not keep on growing during this time!</li>
<li>Remember to tell patients on the everyday pill to start the new packed on day 22</li>
</ul>
<h4><b>Length of prescription</b></h4>
<ul>
<li>Normally when first prescribed, given for 3 months. After this time, BP will be checked, and if no problems or additional RF’s, then will be prescribed for <b>1 year at a time. </b></li>
</ul>
<div></div>
<h4><b>Commencing treatment</b></h4>
<p><b><span style="color: red;">No Previous contraception</span></b></p>
<ul>
<li>Start on day 1 of cycle, OR</li>
<li>If starting after day 4 of cycle, use extra method (e.g. <a class="ilgen" href="/encyclopedia/condoms">condom</a>) for first 7 days</li>
</ul>
<p><b><span style="color: red;">Changing from progesterone only pill</span></b></p>
<ul>
<li>Start on first day of cycle, OR</li>
<li>If <a class="ilgen" href="/encyclopedia/amenorrhoea">amenorrhoea</a>, <b><i>exclude pregnancy </i></b>then start on any day</li>
</ul>
<p><b><span style="color: red;">After child birth</span></b></p>
<ul>
<li>If not breastfeeding, start 3 weeks after birth (otherwise, ↑risk of thrombosis)</li>
<li>If started after 3 weeks, other methods of contraception (e.g. condoms) required for first 7 days.</li>
<li><b><i>DO NOT USE IN BREASTFEEDING – </i></b>alters lactation</li>
</ul>
<p><b><span style="color: red;">After miscarriage / abortion</span></b></p>
<ul>
<li>If less than 24 weeks, start pills straight away. If &gt;24 weeks, seek advice</li>
</ul>
<div></div>
<h4><b>Examples</b></h4>
<ul>
<li><b><i><span style="color: #0070c0;">Microgynon</span></i></b></li>
<li><b><i><span style="color: #0070c0;">Qlaira</span></i></b></li>
</ul>
<div></div>
<h2><b>Alternative preparations</b></h2>
<h3><b>Skin patch </b></h3>
<ul>
<li>May have a higher risk of thromboembolism than the oral preparation</li>
<li>Treatment consists of three patches. First patch applied on day 1 of cycle, second on day 8, and third on day 15. Remove old patch each time, and remove third patch on day 22, and have a week with no patch.</li>
<li>If the first patch is applied on any day other that day 1, another method of contraception (e.g. condoms) need to be used for 7 days</li>
<li><b><i>Withdrawal bleeding occurs during patch-free week</i></b></li>
</ul>
<p>&nbsp;</p>
<h3><b>Vaginal contraceptive ring</b></h3>
<ul>
<li>A small rubber ring that can be inserted into the vagina by the patient, and then sits around the cervix. Stays in place for 3 weeks. Remove after 3 weeks, and have 1 week without ring present (similar to pill and patch)</li>
<li><b><i>Withdrawal bleeding occurs during ring-free week</i></b></li>
</ul>
<p>The post <a href="https://almostadoctor.co.uk/encyclopedia/pills-and-similar-preparations">Contraception &#8211; Combined Oral Contraceptive Pill &#8211; COCP</a> appeared first on <a href="https://almostadoctor.co.uk">almostadoctor</a>.</p>
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		<post-id xmlns="com-wordpress:feed-additions:1">1474</post-id>	</item>
		<item>
		<title>Culture and Contraception</title>
		<link>https://almostadoctor.co.uk/encyclopedia/religion-and-contraception</link>
					<comments>https://almostadoctor.co.uk/encyclopedia/religion-and-contraception#respond</comments>
		
		<dc:creator><![CDATA[Dr Tom Leach]]></dc:creator>
		<pubDate>Wed, 14 Jun 2017 14:27:07 +0000</pubDate>
				<category><![CDATA[Obstetrics and Gynaecology]]></category>
		<category><![CDATA[Sexual Health]]></category>
		<category><![CDATA[Contraception]]></category>
		<guid isPermaLink="false">http://almostadoctor.co.uk/?post_type=encyclopedia&#038;p=1396</guid>

					<description><![CDATA[<p>Introduction When discussing contraception with any patient, it may be useful to understand a little about the patient’s cultural and / or religious background. Obviously, it is not the medical professional’s role to advise on any religious aspects, but only to advise on the medical basis of contraceptive methods, and their use and efficacy, thus [&#8230;]</p>
<p>The post <a href="https://almostadoctor.co.uk/encyclopedia/religion-and-contraception">Culture and Contraception</a> appeared first on <a href="https://almostadoctor.co.uk">almostadoctor</a>.</p>
]]></description>
										<content:encoded><![CDATA[<h3><strong>Introduction</strong></h3>
<div>When discussing <a class="ilgen" href="/encyclopedia/contraception">contraception</a> with any patient, it may be useful to understand a little about the patient’s cultural and / or religious background.</div>
<div></div>
<div>Obviously, it is not the medical professional’s role to advise on any religious aspects, but only to advise on the medical basis of contraceptive methods, and their use and efficacy, thus that the patient may make their own informed decision.</div>
<div><em>It can be a difficult decision for patients, when their religious beliefs and personal views on contraception are at odds.</em></div>
<div></div>
<div>For most religions, the use of contraception is acceptable, although in almost all cases there are different interpretations within the same religious group.</div>
<div></div>
<h3><b>Hinduism</b></h3>
<div><b><i><span style="color: #00b050;">The use of contraception is not discouraged – </span></i></b>in many cases it is actively encouraged, as many Hindu’s believe they have a duty not to produce more children than their environment can support</div>
<div></div>
<h3><b>Sikhism</b></h3>
<div><b><i><span style="color: #00b050;">The decision to use contraception is left to individual couples</span></i></b></div>
<div></div>
<h3><b>Judaism</b></h3>
<div><b><i><span style="color: #00b050;">The use of contraception is generally not discouraged – </span></i></b>some Orthodox groups may suggest that contraception should not be used unless there are certain conditions (e.g. the family already has several children, or <a class="ilgen" href="/encyclopedia/normal-physiology-of-pregnancy">pregnancy</a> may be dangerous to the woman), whilst other groups often will not discourage the use of contraception. Jews may seek advice from their Rabbi, who will give personalised advice.</div>
<ul>
<li>In Orthodox Judaism, hormonal methods may be preferred, as they are perceived as more ‘natural’ than <a href="https://almostadoctor.co.uk/encyclopedia/condoms">barrier methods</a>.</li>
<li>Calendar based methods are discouraged, as they typically co-inside with ‘Niddah’ (days when the women is menstruating).</li>
</ul>
<div></div>
<div><b>Islam</b></div>
<div><b><i><span style="color: #00b050;">Generally, the use of contraception is acceptable</span></i><span style="color: #00b050;"> – </span></b>although <a class="ilgen" href="/encyclopedia/sterilisation">sterilisation</a> may be discouraged.</div>
<div>In some Islamic states (e.g. Iran) contraceptive methods are actively taught to young unmarried people, and to married couples.</div>
<ul>
<li>The views on contraception grew from the historical use of the ‘withdrawal method’, which was widely accepted in Islam. Thus as newer methods have become available, as contraception was already accepted, so were the new methods.</li>
</ul>
<div><b> </b></div>
<h3><b>Christianity</b></h3>
<div><b><i><span style="color: #00b050;">Generally accepted, except in Roman Catholicism. </span></i></b></div>
<div>Generally, the use of contraception is acceptable to most Protestant groups, and to Anglicans.</div>
<div><b><span style="color: red;">The Roman Catholic View</span></b></div>
<ul>
<li><b><i><span style="color: #0070c0;">Even within those who would consider themselves Catholic, the uptake for the use of Natural Family Planning (NFP) is very low </span></i></b><i>(one study suggested 1 in 25 Catholics). </i></li>
<li>The Roman Catholic Church has traditionally forbidden all types of contraception through history. <i>The only acceptable method to the Church, is <b>abstinence. </b></i></li>
<li>In light of this, the Church recommends the use of <b><i>Natural family planning </i></b>to anticipate when the woman is least fertile.
<ul>
<li>These methods are sometimes used outside of the Catholic context, in which case it is usually called <i><span style="color: red;">fertility-awareness based contraception.</span></i></li>
</ul>
</li>
<li><b><i>Natural family planning </i></b>can involve:
<ul>
<li><b><span style="color: #0070c0;">Symptom analysis – </span></b>the <b><i>basal body temperature </i></b>can be used to measure the time of the cycle. This is the lowest temperature attained by the body during rest. It is best measured <b><i>as soon as the woman wakes in the morning. </i></b>It varies between 36.4’ and 36.7’ during the <a class="ilgen" href="/encyclopedia/the-menstrual-cycle">menstrual cycle</a></li>
<li><i><span style="color: #0070c0;">This temperature is also often monitored by women when trying to conceive. </span></i></li>
<li><span style="color: red;">It is suggested that pregnancy is unlikely to result after the third day after ovulation – </span>thus the third day after the increase in temperature.</li>
</ul>
</li>
</ul>
<div class="rtecenter"><b> <img fetchpriority="high" decoding="async" src="/sites/all/files/image/Systems/Obs%20&amp;%20Gyn/Untitled.png" alt="" width="411" height="132" align="middle" /></b></div>
<div><b> </b></div>
<ul>
<li>Other symptoms, such as cervical position and cervical mucus may also be measured to help determine the day of the cycle. Once the day of the cycle has been determined, then the couple can chose to only have sexual intercourse during the least fertile period of the cycle.
<ul>
<li><b><i>Typically, for pregnancy to occur, the sperm much reach the egg within 24 hours after ovulation. </i></b>However, sperm can survive inside the female for up to 7 days.</li>
<li><b><span style="color: #0070c0;">The calendar method – </span></b>the woman needs to carefully monitor her cycle length, and can use this to determine the most fertile period, by knowing that this occurs typically 12-16 days <b><i>before the next predicted menstruation. </i></b>This means the least fertile period is typically around the time of menstruation.</li>
</ul>
</li>
<li><b><span style="color: red;">Efficacy of Natural Family Planning</span></b>
<ul>
<li>Studies show that this varies from between 85-95% per year, and that the highest efficacy rates are in Developed countries, suggesting that thorough education of the individuals who wish to use this method, results in increased efficacy.</li>
</ul>
</li>
<li><b><span style="color: #0070c0;">‘Persona’ – </span></b>is a brand of urine <a class="ilgen" href="/encyclopedia/urine-dipstick">dipstick</a>, used to analyse hormonal changes in the urine. It costs about £65, and dipstick refills cost £10. With a sample of urine it gives a red or a green light, designed to inform the patient whether pregnancy is likely or unlikely if sex occurs at that time.</li>
<li><b><i><span style="color: red;">If the device is used correctly, the risk of pregnancy during the course of 1 year is around 10%</span></i></b></li>
</ul>
<p>The post <a href="https://almostadoctor.co.uk/encyclopedia/religion-and-contraception">Culture and Contraception</a> appeared first on <a href="https://almostadoctor.co.uk">almostadoctor</a>.</p>
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		<post-id xmlns="com-wordpress:feed-additions:1">1396</post-id>	</item>
		<item>
		<title>Sterilisation</title>
		<link>https://almostadoctor.co.uk/encyclopedia/sterilisation</link>
					<comments>https://almostadoctor.co.uk/encyclopedia/sterilisation#respond</comments>
		
		<dc:creator><![CDATA[Dr Tom Leach]]></dc:creator>
		<pubDate>Wed, 14 Jun 2017 13:51:31 +0000</pubDate>
				<category><![CDATA[Obstetrics and Gynaecology]]></category>
		<category><![CDATA[Sexual Health]]></category>
		<category><![CDATA[Contraception]]></category>
		<guid isPermaLink="false">http://almostadoctor.co.uk/?post_type=encyclopedia&#038;p=1304</guid>

					<description><![CDATA[<p>Introduction Can be controversial in some cultures Should only be undertaken in stable relationships where the couple is certain they do not want any more children Epidemiology Rates falling in developed countries UK is unusual as the number of men receiving the operation is greater than the number of women 18% of men between 18-69 [&#8230;]</p>
<p>The post <a href="https://almostadoctor.co.uk/encyclopedia/sterilisation">Sterilisation</a> appeared first on <a href="https://almostadoctor.co.uk">almostadoctor</a>.</p>
]]></description>
										<content:encoded><![CDATA[<h3><b>Introduction</b></h3>
<ul>
<li>Can be controversial in some cultures</li>
<li>Should only be undertaken in stable relationships where the couple is certain they do not want any more children</li>
</ul>
<div></div>
<h3><b>Epidemiology</b></h3>
<p>Rates falling in developed countries<br />
UK is unusual as the number of men receiving the operation is greater than the number of women</p>
<ul>
<li>18% of men between 18-69 have had a vasectomy
<ul>
<li>Only 64% of these were done on the NHS</li>
<li>95% of female sterilisations are performed on the NHS</li>
</ul>
</li>
</ul>
<div></div>
<h3><b>Consent</b></h3>
<div>It is unlikely that anyone with the following situation will be sterilised:</div>
<ul>
<li>Under 30</li>
<li>No children</li>
<li>Not in a long-term relationship</li>
</ul>
<div></div>
<div>Counselling is usually given to all parties. It is not necessary to have the partners permission, but it the patient is encouraged to involve them in the decision making process.</div>
<div></div>
<h3><b>Reversal</b></h3>
<div>Is possible, but is less likely the longer the patients has been sterilised. It not usually available on the NHS.</div>
<p><b><i><span style="color: #0070c0;">The procedure should be treated as irreversible – </span></i></b><i>and discussed as such with the patient. For example, you should point out that if unseen circumstanced were to occur, whereby their current children were to become ill or die, they would be unable to have further children. </i><br />
<b><i><span style="color: #0070c0;">Instances where couples are likely to express regret:</span></i></b></p>
<ul>
<li><i>Under 25</i></li>
<li><i>Fewer than 2 children</i></li>
<li><i>Unstable relationship</i></li>
<li><i>Vasectomy during a partner’s <a href="/encyclopedia/normal-physiology-of-pregnancy" class="ilgen">pregnancy</a></i></li>
<li><i>Tubal ligation at <a href="/encyclopedia/caesarian-section" class="ilgen">C-section</a></i></li>
<li><i><a href="/encyclopedia/sterilisation" class="ilgen">Sterilisation</a> at TOP</i></li>
</ul>
<div></div>
<h3><b>Failure</b></h3>
<div>Like all surgery, there is a small proportion of operations that fail.</div>
<div></div>
<div><b><span style="color: red;">Choosing – </span></b><i>vasectomy or female sterilisation</i></div>
<div><b>Vasectomy is:</b></div>
<ul>
<li>30x less likely to fail</li>
<li>20x less likely to result in complications</li>
<li>Less invasive</li>
<li>Performed under local anaesthetic, and thus is a more minor procedure. Usually a day case.</li>
</ul>
<div></div>
<h3><b>Threat of pregnancy to the mother</b></h3>
<div>Some diseases pose a risk to the mother’s life if she were to become <a href="/encyclopedia/dystocia" class="ilgen">pregnant</a>, for example <b><i>Primary pulmonary <a href="/encyclopedia/diagnosis-pathology-and-management-of-hypertension" class="ilgen">hypertension</a>. </i></b>In this condition, pregnancy could be fatal, and hormonal contraceptives may be contra-indicated. It would be in the woman’s best interest to be sterilised.</div>
<ul>
<li>It is not a good idea to perform vasectomy on the partner in these instances, as it could be possible that the man would be widowed, and left infertile.</li>
</ul>
<div></div>
<h3><b>Female sterilisation</b></h3>
<div><b><i>Tubal occlusion / Tubal ligation / Salpingectomy</i></b></div>
<div></div>
<h4><b>Efficacy</b></h4>
<div>Efficacy rates vary from 99.2 – 99.5%. The <b><i>Filshie clip </i></b>is thought to be the most effective.</div>
<ul>
<li><b><span style="color: #0070c0;">The ‘lifetime failure rate’ – </span></b><i>is about 1 in 200</i></li>
<li><b><i>If the surgery fails, there is an increased risk of <a href="/encyclopedia/ectopic-pregnancy" class="ilgen">ectopic</a> pregnancy</i></b></li>
</ul>
<div>Failure of the procedure can be immediate, or years later.</div>
<div>It can be done laparoscopically (usually local anaesthetic) or as open surgery (general anaesthetic).</div>
<div></div>
<h4><b>Procedure</b></h4>
<ul>
<li>Usually carried out at the <b><i>isthsmus </i></b>(the bit next to the uterus)</li>
<li>The ovaries and uterus are left intact
<ul>
<li><i><span style="color: #0070c0;">Ovulation may still occur, but the ovum is absorbed by surrounding tissues</span></i></li>
</ul>
</li>
<li>May be laparotomy or laparoscopy.</li>
<li><b><i><span style="color: red;">Salpingectomy – </span></i></b><i>is a particular procedure where the tubes are cut, and then sutured over. </i></li>
<li><b><i><span style="color: red;">Clips –</span></i></b> <i>some surgeons prefer to clip, rather than suture the tubes. </i>The clip inhibits blood flow to the clipped area, and the region typically undergoes <a href="/encyclopedia/interstitial-lung-disease-pulmonary-fibrosis" class="ilgen">fibrosis</a> and scarring which help to block the passage.</li>
<li><b><i><span style="color: red;">Rings –</span></i></b> <i>similar to a clip</i></li>
<li><b><i><span style="color: red;">Cauterization</span></i></b></li>
<li><b>Usually performed under general anaesthetic – </b>however in some situations – e.g. directly after a caesarean, may be performed under local.</li>
</ul>
<div></div>
<h4><b>After Surgery</b></h4>
<ul>
<li>Women can consider themselves infertile <b><i>straight after the procedure – </i></b>but there is a risk of pregnancy in the <a href="/encyclopedia/the-menstrual-cycle" class="ilgen">menstrual cycle</a> immediately prior to the surgery.</li>
</ul>
<div></div>
<h4><b>Complications</b></h4>
<ul>
<li>Laparoscopic surgery may need to be converted to open surgery if there are complications.
<ul>
<li><i>This is more likely in obese patients, and in those with previous abdominal surgery</i></li>
</ul>
</li>
<li>Advise patients to seek urgent medical advice if they have vaginal bleeding, or abdominal pain, to rule out ectopic pregnancy</li>
<li><b><i>Associated with increased need for hysterectomy</i></b></li>
<li>Not associated with increased risk of heavy, irregular periods</li>
</ul>
<div></div>
<h3><b>Male sterilisation</b></h3>
<div><b><i>Vasectomy</i></b></div>
<h4><b>Efficacy</b></h4>
<p>0.3% if there is:</p>
<ul>
<li>Ligation of the vas, PLUS</li>
<li>Cauterisation of the ends, PLUS</li>
<li>Insertion of a fascia between the two ends</li>
</ul>
<p>Around 1% if cauterisation only is used<br />
Late failure occurs in 0.2% of cases</p>
<div></div>
<h4><b>Surgical technique</b></h4>
<ul>
<li>The vas is palpated, and moved as close to the scrotal skin as possible. Local anaesthetic (lidocaine 1-2ml) is administered.</li>
<li>Through a small inscision in the scrotal skin, the vas is identified and clamped in two places, about 5cm apart</li>
<li>A small segment (e.g. 1cm) is removed and sent for histology to confirm it is actually the vas deferens.</li>
<li>Of the two ends, the testicular end is tied back on itself to reduce the risk of anastomosis, and the top end is also occluded, with non-absorbable stitching.
<ul>
<li><i><span style="color: #0070c0;">Some surgeons may insert an artificial fascia between the two ends to further reduce the risk of anastomoses</span></i></li>
</ul>
</li>
<li>Suture up the skin</li>
</ul>
<div></div>
<h4><b>Alternative methods</b></h4>
<ul>
<li>Cauterisation of the vas</li>
</ul>
<div></div>
<h4><b>Measuring success</b></h4>
<ul>
<li>There needs to be <b><i>two negative sperm count samples 1 month apart, </i></b>taken after a <b><i>minimum of 20 ejaculations. </i></b></li>
</ul>
<div></div>
<h4><b>After surgery</b></h4>
<ul>
<li>Normal ejaculation and orgasm occur, however, there is no sperm in the ejaculate.</li>
<li>May be painful, and men advised to take several days off work, and not do anything too strenuous for 1 week</li>
</ul>
<div></div>
<h4><b>Complications</b></h4>
<p><b><span style="color: red;">Bleeding</span></b></p>
<ul>
<li>Mild – 1:400</li>
<li>Major – 1:1000</li>
</ul>
<p><b><span style="color: red;">Infection – </span></b>1:100<br />
<b><span style="color: red;">Epididymitis –</span></b> 1:100<br />
<b><span style="color: red;">Persistent pain –</span></b> 1:1000<br />
<b><span style="color: red;">perm granuloma –</span></b> 1:500</p>
<ul>
<li><i>This is a tender scrotal swelling at the proximal end of the cut vas, and will require excision. </i></li>
</ul>
<div></div>
<div><b><span style="color: red;">Vasectomy does NOT cause:</span></b></div>
<ul>
<li><i>Testicular / <a href="/encyclopedia/prostate-cancer" class="ilgen">prostate cancer</a></i></li>
<li><i>Immune complex disease</i></li>
<li><i><a href="/encyclopedia/atherosclerosis-and-coronary-heart-disease-chd" class="ilgen">Ischaemic heart disease</a></i></li>
<li><i>Loss of libido</i></li>
</ul>
<h3>References</h3>

<p><a href="https://almostadoctor.co.uk/sources">Read more about our sources</a></p>
<p>The post <a href="https://almostadoctor.co.uk/encyclopedia/sterilisation">Sterilisation</a> appeared first on <a href="https://almostadoctor.co.uk">almostadoctor</a>.</p>
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		<post-id xmlns="com-wordpress:feed-additions:1">1304</post-id>	</item>
		<item>
		<title>Contraception &#8211; Hormonal Injections</title>
		<link>https://almostadoctor.co.uk/encyclopedia/hormonal-injections</link>
					<comments>https://almostadoctor.co.uk/encyclopedia/hormonal-injections#respond</comments>
		
		<dc:creator><![CDATA[Dr Tom Leach]]></dc:creator>
		<pubDate>Wed, 14 Jun 2017 10:39:52 +0000</pubDate>
				<category><![CDATA[Obstetrics and Gynaecology]]></category>
		<category><![CDATA[Contraception]]></category>
		<guid isPermaLink="false">http://almostadoctor.co.uk/?post_type=encyclopedia&#038;p=851</guid>

					<description><![CDATA[<p>Introduction The contraceptive injection is a common form of progesterone only contraception given to women. Injections are typically given every 3 months. Hormonal injections and generally considered &#62;99% effective for contraception, but provide no protection against STIs. There can be a slightly erratic return to normal period after the medication is ceased. There is also [&#8230;]</p>
<p>The post <a href="https://almostadoctor.co.uk/encyclopedia/hormonal-injections">Contraception &#8211; Hormonal Injections</a> appeared first on <a href="https://almostadoctor.co.uk">almostadoctor</a>.</p>
]]></description>
										<content:encoded><![CDATA[<h3><b>Introduction</b></h3>
<p>The contraceptive injection is a common form of progesterone only contraception given to women. Injections are typically given every 3 months. Hormonal injections and generally considered &gt;99% effective for contraception, but provide no protection against STIs.</p>
<p>There can be a slightly erratic return to normal period after the medication is ceased. There is also a risk of weight gain compared to some other methods of contraception.</p>
<p>There are two brands available in the UK:</p>
<p><b><span style="color: red;">Depo-Provera – </span></b>administered every 12 weeks</p>
<ul>
<li>Injection of choice</li>
<li>Aka <b><i>Medroxyprogesterone acetate</i></b></li>
</ul>
<p><b><span style="color: red;">Noristerat – </span></b>administered every 8 weeks</p>
<ul>
<li><i><span style="color: #0070c0;">Depo-provera is more effective than Noristerat</span></i></li>
<li><i>Usually only offered as short-term treatment – <b>e.g. for women waiting for <a class="ilgen" href="/encyclopedia/sterilisation">sterilisation</a></b></i></li>
</ul>
<h3><strong>Summary</strong></h3>
<div>
<table>
<tbody>
<tr>
<td>
<div><b>CONTRACEPTION</b></div>
</td>
<td>
<div><b>INJECTABLE PROGESTERONE</b></div>
</td>
</tr>
<tr>
<td>
<div><b>EFFECTIVENESS</b></div>
</td>
<td>
<div>&gt; 99% effective</div>
</td>
</tr>
<tr>
<td>
<div><b>PREPARATIONS</b></div>
</td>
<td>
<div>Depot (every 12 wks) Noristerat (every 8 wks)</div>
</td>
</tr>
<tr>
<td>
<div><b>HOW IT WORKS</b></div>
</td>
<td>
<div>slow release of progesterone into body – thinning endometrium, preventing ovulation and thickening cervical mucus</div>
</td>
</tr>
<tr>
<td>
<div><b>ADVANTAGES</b></div>
</td>
<td>
<div>No oestrogen content</div>
<div>Reduces PID</div>
<div>Can use in Breastfeeding and epileptics</div>
</td>
</tr>
<tr>
<td>
<div><b>DISADVANTAGES</b></div>
</td>
<td>
<div>May cause irregular bleeding – <a class="ilgen" href="/encyclopedia/amenorrhoea">amenorrhoea</a>, irregular , longer</div>
<div>Fertility may take time to return to normal (~10m)</div>
<div>Weight gain ~ 3kg in 1<sup>st</sup> yr</div>
<div>SE = <a class="ilgen" href="/encyclopedia/headache">headache</a>, mood change and breast tenderness , <a class="ilgen" href="/encyclopedia/acne-vulgaris">acne</a> and hirtuism</div>
</td>
</tr>
<tr>
<td>
<div><b>Contra-indications</b></div>
</td>
<td>
<div>Abnormal undiagnosed vaginal bleeding, severe cardiac disease, acute <a class="ilgen" href="/encyclopedia/liver-physiology">liver</a> disease</div>
</td>
</tr>
</tbody>
</table>
<h3><b>Efficacy</b></h3>
<ul>
<li>Quoted as &gt;<b><i><span style="color: #0070c0;">99% effective</span></i></b></li>
<li>Described as: if taken correctly, then during the course of 1 year, &lt;1% of women using the injection will become <a class="ilgen" href="/encyclopedia/dystocia">pregnant</a></li>
</ul>
<h3><b>Mechanism</b></h3>
<p><b>Prevent ovulation – </b>and <b><span style="color: red;">may stop periods</span></b></p>
<ul>
<li>Other methods of <a href="https://almostadoctor.co.uk/encyclopedia/contraception-progesterone-only-pill-pop">progesterone only contraception</a> will often make periods lighter, and may prevent them in some women. However, progestogen injection will be more likely to prevent ovulation and regular menstrual bleeding in a higher proportion of women.</li>
<li>This is the <i>main benefit of this treatment over other options</i></li>
<li><b><i><span style="color: red;">Some women may get heavier or irregular periods</span></i></b></li>
</ul>
<p>Thickens cervical mucus<br />
Alters lining of the uterus, making it difficult for implantation to take place</p>
<div>
<figure id="attachment_7022294" aria-describedby="caption-attachment-7022294" style="width: 300px" class="wp-caption aligncenter"><a href="https://almostadoctor.co.uk/wp-content/uploads/2017/06/depo-provera-injection.jpeg"><img decoding="async" class="size-medium wp-image-7022294" src="https://almostadoctor.co.uk/wp-content/uploads/2017/06/depo-provera-injection-300x225.jpeg" alt="Depo Provera Injection" width="300" height="225" srcset="https://almostadoctor.co.uk/wp-content/uploads/2017/06/depo-provera-injection-300x225.jpeg 300w, https://almostadoctor.co.uk/wp-content/uploads/2017/06/depo-provera-injection-1024x768.jpeg 1024w, https://almostadoctor.co.uk/wp-content/uploads/2017/06/depo-provera-injection-768x576.jpeg 768w, https://almostadoctor.co.uk/wp-content/uploads/2017/06/depo-provera-injection-1536x1152.jpeg 1536w, https://almostadoctor.co.uk/wp-content/uploads/2017/06/depo-provera-injection-2048x1536.jpeg 2048w" sizes="(max-width: 300px) 100vw, 300px" /></a><figcaption id="caption-attachment-7022294" class="wp-caption-text">Depo Provera Injection</figcaption></figure>
</div>
<h3><b>Cautions and contraindications</b></h3>
<p>Should not be first line in women &lt;18 or &gt;45 due to <b><i>risk of reduction in <a href="https://almostadoctor.co.uk/encyclopedia/calcium-vitamin-d-and-bone-density">bone density</a></i></b></p>
<ul>
<li>In women &lt;18 can alter the formation of new bone, as bones are still developing</li>
<li>In women over 45 can increase the rate of bone density reduction</li>
<li><b><i><span style="color: #0070c0;">The reduction in bone density is greatest in the first 2-3 years of use, then stabilises. </span></i></b></li>
</ul>
<p>Should be avoided when other RF’s for <a class="ilgen" href="/encyclopedia/osteoporosis">osteoporosis</a> are present</p>
<ul>
<li><i><span style="color: #0070c0;">Low oestrogen due to amenorrhoea for &gt;6 months – </span>e.g. due to extreme dieting, exercise or <a href="https://almostadoctor.co.uk/encyclopedia/eating-disorders">eating disorder</a></i></li>
<li><i><span style="color: #0070c0;">Smoker</span></i></li>
<li><i><span style="color: #0070c0;">Heavy drinker</span></i></li>
<li><i><span style="color: #0070c0;">Long-term steroid use</span></i></li>
<li><i><span style="color: #0070c0;">FH of osteoporosis </span>(1<sup>st</sup> degree relatives)</i></li>
</ul>
<div><b> </b></div>
<h3><b>Side effects</b></h3>
<ul>
<li>Bleeding may be heavier for the first 3-4 months, but will usually settle down, and most women ultimately do not have periods</li>
<li>Mood swings</li>
<li><span style="font-style: italic;"><span style="font-weight: bold;">Reduction in bone density / increased risk of osteoporosis in later life</span></span></li>
<li><b><span style="color: red;">Weight gain – </span></b>typically 2-3Kg per year</li>
</ul>
<div></div>
<h3><b>Benefits over oral POP</b></h3>
<p>More likely to inhibit ovulation, thus:</p>
<ul>
<li>Less likelyhood of periods</li>
<li>Recued risk of ovarian cysts and <a class="ilgen" href="/encyclopedia/ectopic-pregnancy">ectopic</a> <a class="ilgen" href="/encyclopedia/normal-physiology-of-pregnancy">pregnancy</a></li>
<li>Also, <b><i><span style="color: red;">no interaction with non-enzyme inducing antibacterials</span></i></b></li>
</ul>
<div></div>
<h3><b>Drug interactions</b></h3>
<p><b><span style="color: #0070c0;">Enzyme-inducing drugs</span></b></p>
<ul>
<li>E.g. St John’s Wort</li>
<li><a class="ilgen" href="/encyclopedia/tb-tuberculosis">TB</a>, <a class="ilgen" href="/encyclopedia/epilepsy">epilepsy</a> and <a class="ilgen" href="/encyclopedia/hiv-and-hiv-counselling">HIV</a> medications</li>
<li><i>If the patient also takes any of these, it is recommended to use additional contraception (e.g. <a class="ilgen" href="/encyclopedia/condoms">condoms</a>) for the duration of the treatment and for <b>4 weeks</b> after</i></li>
</ul>
<div></div>
<h3><b>Prescribing and administration</b></h3>
<p>Given IM, usually into the gluteal muscles. <b><i>Depo-provera </i></b>may be given in the leg or arm</p>
<ul>
<li><b>Noristat is a more viscous solution and may be more painful during administration</b></li>
</ul>
<p>If there is any chance of pregnancy, the patient <b><i><span style="color: red;">must have a pregnancy test before commencing treatment. </span></i></b></p>
<ul>
<li><i><span style="color: #0070c0;">Administration during pregnancy can masculinise the fetus</span></i></li>
</ul>
<p>Treatment should be commenced within 5 days of the start of the cycle</p>
<ul>
<li>If started at any other day in the cycle, another method of contraception (e.g. condoms) should be used for the first 7 days.</li>
</ul>
<p><b><span style="color: red;">After pregnancy</span></b></p>
<ul>
<li><span style="font-family: 'Courier New';">o<span style="font: 7pt 'Times New Roman';">   </span></span>Usually started 6 weeks after pregnancy. This reduces the risk of heavy / irregular periods.
<ul>
<li>Can be given after 21 days on request</li>
<li>If given at 6 weeks, then an alternative form of contraception (e.g. condoms) should be used between 21 days and 6 weeks</li>
<li>Pregnancy cannot occur in the first 21 days after the birth of a previous child</li>
</ul>
</li>
</ul>
<p><b><span style="color: red;">After miscarriage / abortion</span></b></p>
<ul>
<li>Treatment can be started immediately, and will be immediately effective</li>
</ul>
<h3><b>General advice</b></h3>
<ul>
<li>Breast-feeding is not affected</li>
<li><b>Missing an injection</b></li>
<li>You can be up to two weeks late for the next appointment, and still be fully ptorected:
<ul>
<li>i.e. 10 weeks for Noristerat</li>
<li>14 weeks for Depo-Provera</li>
</ul>
</li>
<li><b>Duration of treatment &#8211; </b>Providing there are no contra-indications, or RF’s for osteoporosis, treatment can be continued until menopause</li>
<li><b>topping treatment</b>
<ul>
<li>Fertility can take several months to return after treatment is stopped.</li>
<li>Important to <b><i>warn patients they can get pregnant after cessation of treatment but before their first normal period. </i></b></li>
</ul>
</li>
</ul>
<h3>References</h3>
<ul>
<li>Murtagh’s General Practice. 6th Ed. (2015) John Murtagh, Jill Rosenblatt</li>
<li>Oxford Handbook of General Practice. 3rd Ed. (2010) Simon, C., Everitt, H., van Drop, F.</li>
<li>Beers, MH., Porter RS., Jones, TV., Kaplan JL., Berkwits, M. The Merck Manual of Diagnosis and Therapy</li>
</ul>

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</div>
<p>The post <a href="https://almostadoctor.co.uk/encyclopedia/hormonal-injections">Contraception &#8211; Hormonal Injections</a> appeared first on <a href="https://almostadoctor.co.uk">almostadoctor</a>.</p>
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		<post-id xmlns="com-wordpress:feed-additions:1">851</post-id>	</item>
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		<title>Emergency Contraception</title>
		<link>https://almostadoctor.co.uk/encyclopedia/emergency-contraception</link>
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		<dc:creator><![CDATA[Dr Tom Leach]]></dc:creator>
		<pubDate>Tue, 13 Jun 2017 13:07:39 +0000</pubDate>
				<category><![CDATA[Obstetrics and Gynaecology]]></category>
		<category><![CDATA[Contraception]]></category>
		<guid isPermaLink="false">http://almostadoctor.co.uk/?post_type=encyclopedia&#038;p=708</guid>

					<description><![CDATA[<p>Introduction Emergency contraception is an important post-coital method of contraception to prevent pregnancy from occurring. The risk of pregnancy is highest during the 6 days prior to ovulation, and on the day of ovulation Ovulation can be variable and unpredictable but is typically around day 14 of the cycle Emergency contraception methods do not cause [&#8230;]</p>
<p>The post <a href="https://almostadoctor.co.uk/encyclopedia/emergency-contraception">Emergency Contraception</a> appeared first on <a href="https://almostadoctor.co.uk">almostadoctor</a>.</p>
]]></description>
										<content:encoded><![CDATA[<h3><strong>Introduction</strong></h3>
<div>Emergency contraception is an important post-coital method of contraception to prevent pregnancy from occurring.</div>
<div>
<ul>
<li>The risk of pregnancy is highest during the 6 days prior to ovulation, and on the day of ovulation</li>
<li>Ovulation can be variable and unpredictable but is typically around day 14 of the cycle</li>
</ul>
</div>
<div>Emergency contraception methods <b>do not cause abortion. </b>Instead, they prevent ovulation, fertilisation, and/or implantation. There are three methods by which this can occur:</div>
<ul>
<li>Oral progesterone-only emergency contraception (POEC) &#8211; <strong>levonorgestrel (LNG)</strong>
<ul>
<li>The traditional &#8216;morning after pill&#8217;. More effective the sooner it is taken. Should be taken within 72 hours of intercourse.</li>
<li><em><strong>Pregnancy rate if taken within 120 hours &#8211; 2.2%</strong></em></li>
</ul>
</li>
<li>Selective progesterone receptor modulator (SPRM) &#8211; <strong>ulipristal acetate (UPA)</strong>
<ul>
<li>A newer drug &#8211; widely used in Australia &#8211; use may be more limited in UK</li>
<li>More effective than levonorgestrel and can be used up to 120 hours (5 days) after unprotected sex</li>
<li><em><strong>Pregnancy rate if taken within 120 hours &#8211; 1.4%</strong></em></li>
</ul>
</li>
<li>Copper intra-uterine contraceptive device (<a href="https://almostadoctor.co.uk/encyclopedia/intrauterine-iud"><strong>Copper </strong><strong>IUD</strong></a>)
<ul>
<li>Intra-uterine device is the most effective method (99% effective), and should be offered to all women, even those presenting after 72 hours</li>
<li>The IUS (intrauterine system) aka progesterone containing intrauterine system (e.g. <em><strong>mirena</strong></em><em>) </em>is NOT indicated</li>
<li><em><strong>Pregnancy rate if taken within 120 hours &#8211; &lt;1%</strong></em></li>
</ul>
</li>
</ul>
<div>In the UK, the emergency contraceptive pill (levonorgestrel) is provided free of charge at most health care centres (e.g. GUM clinics, GP’s). You can also buy it at most pharmacies, if you are over 16 (~£25) without a prescription.</div>
<div>
<ul>
<li>In Australia both LNG and UPA are available without prescription over the counter in pharmacies</li>
</ul>
</div>
<div>It is important to counsel women about the available options &#8211; remembering to including the copper coil &#8211; as it is under-utilised and the most effective method &#8211; and is especially recommended at the high risk time around ovulation, when the pill methods are much less effective.</div>
<div></div>
<div>None of the methods should be used when a known pregnancy is present (i.e. implantation has already occurred).</div>
<div></div>
<h3>Assessment and History</h3>
<ul>
<li>Document date of LMP (last menstrual period)</li>
<li>Ask about:
<ul>
<li>Timing of unprotected sexual intercourse
<ul>
<li>If &gt;72 hours &#8211; IUD or ulipristal recommended, &lt;72 hours any of the three options</li>
</ul>
</li>
<li>Current contraceptive methods
<ul>
<li>If on the pill, ask about missed pills</li>
<li>May be appropriate to talk about proper use of barrier methods and assess if they are being used correctly</li>
</ul>
</li>
<li>Possibility of non-consensual sex and offer support and referral if appropriate</li>
</ul>
</li>
<li><em>Remember: there is no time in the menstrual cycle where there is no risk of pregnancy. The risk is lowest in the first 3 days. </em></li>
<li>Important to advise the patient that:
<ul>
<li>Methods are not 100% effective</li>
<li>Their next period may be early or late</li>
<li>They should have a pregnancy test if their next period is &gt;7 days late</li>
<li>They should see a doctor immediately if they develop lower abdominal pain</li>
<li>They should consider ongoing long-term contraceptive options</li>
<li>Discuss the risk of STI &#8211; and consider sexual health screening</li>
</ul>
</li>
<li>As well as emergency contraception &#8211; don&#8217;t forget to offer ongoing long-term contraception</li>
</ul>
<h3><b>Emergency oral preparations</b></h3>
<div>More effective the sooner they are taken.</div>
<div>Both pill methods work by <em><strong>preventing ovulation</strong></em><strong> </strong>by preventing the <strong>LH </strong><strong>surge </strong>which typically occurs just before ovulation. <strong>HOWEVER &#8211; </strong>this means that if ovulation has occurred &#8211; they are not effective. This is important to remember when prescribing. Ovulation typically occurs around day 14 of the cycle &#8211; if the women presents at this time &#8211; consider copper coil.</div>
<h4>Levonorgestrel</h4>
<p>The same progestrogen found in the IUS (Mirena). It is a progestrogen only pill. Thus it is safe in breastfeeding, and for women in whom oestrogens are contraindicated.</p>
<p><strong>Dose &#8211; </strong>1.5mg</p>
<ul>
<li>Consider 3mg dose if raised BMI (&gt;26) or on liver-enzyme inducing medications
<ul>
<li>Phenytoin and carbamazepine are likely the most commonly seen examples</li>
<li>Raised BMI reduces the efficacy of LNG</li>
</ul>
</li>
<li><i>In emergency situations when only 30mcg levonorgestrel pills are available (e.g. the <a href="https://almostadoctor.co.uk/encyclopedia/contraception-progesterone-only-pill-pop">progesterone-only contraceptive pill</a> such as Microlut) &#8211; this may be taken as an alternative &#8211; but <strong>25 tablets (!) will need to be taken TWICE &#8211; 12 hours apart </strong>&#8211; for a total of 50 tablets.</i></li>
</ul>
<p><strong>Contraindications</strong></p>
<ul>
<li>Severe <a href="https://almostadoctor.co.uk/encyclopedia/clinical-consequences-of-liver-disease">liver disease</a></li>
<li>Known allergy to levonorgestrel</li>
</ul>
<p><b>Side effects</b></p>
<ul>
<li>Menstrual irregularities</li>
<li><i><span style="color: #0070c0;">For most women the next period will be normal, but it can be 2-7 days late. </span></i></li>
<li><i>There may be irregular bleeding during the next <a class="ilgen" href="/encyclopedia/the-menstrual-cycle">menstrual cycle</a></i></li>
<li>Nausea</li>
<li>Vomiting</li>
<li>Breast tenderness</li>
</ul>
<p><b>Efficacy</b></p>
<ul>
<li>Most effective within 12 hours after sexual intercourse</li>
<li>95% if &lt;24h</li>
<li>85% if 24-48h</li>
<li>58% if 49-72h</li>
<li>May be given up to 120h, but is not recommended. Between 72-120h, an <a class="ilgen" href="/encyclopedia/coils-iud-and-ius">IUD</a> or ulipristal is recommended as they are more effective</li>
</ul>
<p><b>Vomiting</b></p>
<ul>
<li>If vomiting occurs within 2 hours of administration, another pill should be given. If vomiting continues, consider IUD, or consider another dose, with an <a class="ilgen" href="/encyclopedia/antiemetics">antiemetic</a> (<b><i>domperidone recommended</i></b>).</li>
<li>Another form of contraception &#8211; e.g. COCP or POP can be started immediately</li>
</ul>
<p><b>Prescribing</b></p>
<p>Can be taken as many times as necessary, even within the same menstrual cycle however, not recommended, as it is not as reliable as regular <a class="ilgen" href="/encyclopedia/contraception">contraception</a>.</p>
<p><em><strong>A barrier</strong></em><i style="font-weight: bold;"> method of contraception </i>needs to be used for 7 days (COCP), or 3 days for POCP.</p>
<ul>
<li>If due to missed oral contraceptive pill advise to take the next one within 12 hours of taking levonorgestrel &#8211; but re-iterate she will need to use barrier contraceptive for the time periods outlined above</li>
</ul>
<p>If there is any lower abdominal pain before the next period, she should <b><i>consult immediately </i></b>to rule out <a class="ilgen" href="/encyclopedia/ectopic-pregnancy">ectopic</a> <a class="ilgen" href="/encyclopedia/normal-physiology-of-pregnancy">pregnancy</a><br />
If she has any concerns (e.g. if next period is late, could be <a class="ilgen" href="/encyclopedia/dystocia">pregnant</a>) to seek medical advice.</p>
<h4>Ulipristal Acetate</h4>
<p><strong>Dose</strong></p>
<ul>
<li>30mg as soon as possible after intercourse. Should not be used &gt;120 hours after intercourse</li>
<li>Should not be used more than once in one menstrual cycle</li>
<li>The only oral method licensed for use between 72 and 120 hours</li>
</ul>
<p><b>Contraindications</b></p>
<ul>
<li>Contraindicated in uncontrolled <a class="ilgen" href="/encyclopedia/asthma">asthma</a></li>
<li>Avoid breast-feeding for 36 hours (precautionary, no evidence)
<ul>
<li>LNG and copper coil are both safe with breast-feeding</li>
</ul>
</li>
<li>Severe liver disease</li>
</ul>
<p><strong>Efficacy</strong></p>
<ul>
<li>More effective than LNG, but less effective than copper coil
<ul>
<li>Efficacy also reduced by increased BMI, but not to the same extent as LNG and the dose does NOT alter</li>
</ul>
</li>
</ul>
<p><strong>Side effects</strong></p>
<ul>
<li>Reduces efficacy of <a class="ilgen" href="/encyclopedia/pills-and-similar-preparations">COC</a> and POP
<ul>
<li>As such, when (re-)starting long term progestogen containing contraceptives &#8211; patients need to wait 5 days before starting &#8211; <strong>AND </strong>then use a barrier method until the long-term contraceptive method becomes effective</li>
</ul>
</li>
<li><b>Side effects &#8211; </b>GI disturbance, dizziness, fatigue, <a class="ilgen" href="/encyclopedia/headache">headaches</a>, menstrual irregularities</li>
<li>Advise repeat dose of vomiting within 3 hours of taking (note this timeframe is different for LNG)</li>
</ul>
<div></div>
<h3><b>IUD (copper coil) as emergency contraception</b></h3>
<ul>
<li><b><i><span style="color: red;">More effective than levonorgestrel &#8211; </span></i></b><i>around 99% effective</i></li>
<li>Maintains its efficacy right up until 5 days after sexual intercourse</li>
<li>Copper has multiple effect on the fertilisation and implantation process
<ul>
<li>Inhibits sperm penetration of cervical mucus</li>
<li>Toxic effects on the ovum</li>
<li>Inflammatory reaction effects on the endometrium prevent implantation</li>
</ul>
</li>
<li>Effective up to 5 days after intercourse
<ul>
<li><b><i><span style="color: #00b050;">Ensure that the patient has only had <span style="text-decoration: underline;">unprotected</span> sex <span style="text-decoration: underline;">once</span> since the last period – </span></i></b>if not, the IUD is only effective if fitted within 5 days of the earliest date of ovulation.</li>
</ul>
</li>
<li>Also provides ongoing contraception for up to 10 years</li>
<li>Is not affected by diarrhoea or malabsorption</li>
<li><b>Efficacy &#8211; </b>99% effective</li>
<li><b>Risk factors and side effects – </b>same as the IUD in normal circumstances
<ul>
<li>Remember; risk of infection within 20 days of fitting, and increased risk of PID. Recommended to perform sexual health screening at time of insertion</li>
</ul>
</li>
<li><b>Fitting – </b>same as IUD in normal circumstances, <b><i>except:</i></b>
<ul>
<li><i><span style="color: #0070c0;">Swabs for STI recommended to be taken in <b>all instances</b></span></i></li>
<li><b><i><span style="color: #0070c0;"><a class="ilgen" href="/encyclopedia/antibiotics-drug-classes-and-mechanisms">Antibiotic</a> prophylaxis may be given at the time of insertion if deemed to be high risk for PID: </span></i></b>age &lt;=25, new sexual partner, &gt;1 sexual partner in last 12 months</li>
</ul>
</li>
<li><b>Next period – </b>should be at the normal time</li>
<li><b>Follow up –</b>same as IUD in normal circumstances. Check up at 3-6 weeks. IUD can then be removed if the patient does not wish to use it as a form of long term contraception</li>
<li><em><strong>NB &#8211; Mirena </strong></em>(progesterone containing IUD) is <strong>NOT </strong>indicated for emergency contraception</li>
</ul>
<h3>Ethics</h3>
<p><em>Those who believe life begins at fertilisation may argue that abortion can occur with these methods, and may have moral objections. However, the methods do not cause any alteration to an embryo after implantation.</em></p>
<ul>
<li><em>In the UK, a 2002 Judicial Review concluded that &#8211; legally &#8211; life begins at implantation and not at fertilisation.</em></li>
</ul>
<h3>References</h3>
<ul>
<li><a href="https://actsnsw.communityhealthpathways.org/55831.htm">Emergency Contraception &#8211; Helath Pathways ACT</a></li>
<li><a href="https://patient.info/doctor/emergency-contraception-pro">Emergency Contraception &#8211; patient.info</a></li>
<li>Murtagh’s General Practice. 6th Ed. (2015) John Murtagh, Jill Rosenblatt</li>
<li>Oxford Handbook of General Practice. 3rd Ed. (2010) Simon, C., Everitt, H., van Drop, F.</li>
</ul>

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		<title>Contraception &#8211; barrier methods</title>
		<link>https://almostadoctor.co.uk/encyclopedia/condoms</link>
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		<dc:creator><![CDATA[Dr Tom Leach]]></dc:creator>
		<pubDate>Tue, 13 Jun 2017 12:15:53 +0000</pubDate>
				<category><![CDATA[Obstetrics and Gynaecology]]></category>
		<category><![CDATA[Sexual Health]]></category>
		<category><![CDATA[Contraception]]></category>
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					<description><![CDATA[<p>Condoms The condom is a form of barrier contraception, and stops the sperm from reaching the egg. They also provide protection from sexually transmitted infection. Condoms are easily accessible, cheap to buy, and can also be procured free of charge from health care services. They are very good as a barrier to transmission of infection [&#8230;]</p>
<p>The post <a href="https://almostadoctor.co.uk/encyclopedia/condoms">Contraception &#8211; barrier methods</a> appeared first on <a href="https://almostadoctor.co.uk">almostadoctor</a>.</p>
]]></description>
										<content:encoded><![CDATA[<h3>Condoms</h3>
<div>The condom is a form of barrier <a class="ilgen" href="/encyclopedia/contraception">contraception</a>, and stops the sperm from reaching the egg. They also provide protection from sexually transmitted infection.</div>
<div>Condoms are easily accessible, cheap to buy, and can also be procured free of charge from health care services. They are <b><i><span style="color: red;">very good as a barrier to transmission of infection </span></i></b>but not so good when used alone for contraception.</div>
<ul>
<li><b><span style="color: #0070c0;">It is the only form of contraception that protects from STD’s</span></b></li>
<li><b><span style="color: #00b050;">98% effective – </span></b>when used correctly</li>
</ul>
<div></div>
<div>There are many brands of condom available, but patients in the UK should make sure the ones they are using carry the <b><i>British Kite Mark </i></b><i>and / or the CE logo – </i>which proves that a particular brand has passed testing scrutiny.</div>
<div></div>
<div><b><i>Condoms and lube</i></b></div>
<div>Condoms no longer come packaged in a spermicidal gel. It is thought that this added little to their efficacy, and caused irritation and <a class="ilgen" href="/encyclopedia/allergy">allergic</a> reaction in individuals.</div>
<div>They do however often come packaged in lubricant. This is a <b><span style="color: #0070c0;">water based lubricant – </span></b>and oil based lubricants should not be used with condoms as they can damage the condom.</div>
<ul>
<li><i>Other things that can affect the structural integrity of condoms include ice-cream and lipstick!</i></li>
<li>There are condoms specifically produced men who have sex with men (MSM), which are made of thicker rubber, and come with more lubricant.</li>
<li>Most condoms are made from latex, or a thin plastic, e.g. polyisoprene or polyurethane</li>
</ul>
<h3>Female condoms</h3>
<div>Not particularly popular, only one brand available (<i>Femidom). </i>Sits inside the vagina to form an artificial lining.</div>
<ul>
<li><b><span style="color: #00b050;">95% effective &#8211; </span></b>when used correctly</li>
</ul>
<h3>Diaphragm</h3>
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		<post-id xmlns="com-wordpress:feed-additions:1">631</post-id>	</item>
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		<title>Contraception</title>
		<link>https://almostadoctor.co.uk/encyclopedia/contraception</link>
					<comments>https://almostadoctor.co.uk/encyclopedia/contraception#respond</comments>
		
		<dc:creator><![CDATA[Dr Tom Leach]]></dc:creator>
		<pubDate>Tue, 13 Jun 2017 12:09:59 +0000</pubDate>
				<category><![CDATA[Obstetrics and Gynaecology]]></category>
		<category><![CDATA[Sexual Health]]></category>
		<category><![CDATA[Contraception]]></category>
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					<description><![CDATA[<p>Background info 1/3 of pregnancies are unplanned The UK government now promotes long acting reversible contraception (LARC) (e.g. IUD, IUS, implant)as the best method of contraception because: Reduced chance of patient error – e.g. forgetting to take the pill, not using condoms It is also cheaper! – it requires fewer primary health care appointments than [&#8230;]</p>
<p>The post <a href="https://almostadoctor.co.uk/encyclopedia/contraception">Contraception</a> appeared first on <a href="https://almostadoctor.co.uk">almostadoctor</a>.</p>
]]></description>
										<content:encoded><![CDATA[<h3><b>Background info</b></h3>
<ul>
<li>1/3 of pregnancies are unplanned</li>
<li>The UK government now promotes <b><i><span style="color: #0070c0;">long acting reversible <a class="ilgen" href="/encyclopedia/contraception">contraception</a> (LARC) </span></i></b><i>(e.g. <a class="ilgen" href="/encyclopedia/coils-iud-and-ius">IUD</a>, IUS, implant)</i>as the best method of contraception because:
<ul>
<li>Reduced chance of patient error – e.g. forgetting to take the pill, not using <a class="ilgen" href="/encyclopedia/condoms">condoms</a></li>
<li><b><i><span style="color: red;">It is also cheaper! – </span></i></b>it requires fewer primary health care appointments than e.g. the pill, which has to be reviewed every 3-12 months.</li>
</ul>
</li>
<li><b><span style="color: #0070c0;">Prescribing contraception to under 16’s – </span></b>you should do so under the <b><i>Fraser Guidelines </i></b>(aka Gillick competance) – i.e. the doctor should believe that:
<ul>
<li>The patient is able to retain and recall information, and understands advice given</li>
<li>The patient should be encouraged to discuss issues with parents; however in the case that this is not possible, the doctor is still able to proceed</li>
<li>The patient is likely to have an active sexual life anyway, even if contraceptives are not given</li>
<li>The patients mental or physical health may suffer if contraceptives are not given</li>
<li>It is in the patients best interests to receive contraceptives and contraceptive advice, with or without parental consent.</li>
</ul>
</li>
<li><b><span style="color: #0070c0;">Without contraception – </span></b>80-90% of women will become <a class="ilgen" href="/encyclopedia/dystocia">pregnant</a> within a year if having regular sexual intercourse.</li>
<li><b><span style="color: #0070c0;">All methods of contraception are free to all men and women on the NHS</span></b></li>
<li><span style="color: red;">You should always ask if there is any chance the patient is pregnant before commencing contraception! – </span>If there is any doubt, then <b><i>just do the test. </i></b></li>
<li><b><i><span style="color: red;">No contraception is 100% effective!</span></i></b></li>
</ul>
<p>It is important that before any method of hormonal (and also IUD) contraception, the patient is counselled by a trained individual, and provided with information leaflets, and allowed to make their own informed decision.</p>
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