SSRIs – Selective Serotonin Reuptake Inhibitors

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Introduction Selective Serotonin Re-uptake Inhibitors (SSRIs) e.g. fluoxetine, paroxetine, sertraline, citalopram These are the most common used antidepressant. They are: Just as effective as TCAs in mild / moderate depression…

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Thiazide Diuretics

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Introduction Thiazide and thiazide-like diuretics are commonly used for management of hypertension, as well as management of oedema (e.g. in heart failure or liver failure). They are¬†moderately potent¬†diuretics¬†as opposed to…

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Tricyclic Antidepressants

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Introduction Tricyclic Antidepressants¬†e.g. Amitriptyline, imipramine, lofepramine There are also related compounds, that are not technically tricyclics, but that we will consider as the same here: amoxapine, maprotiline Mechanism They inhibit…

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Tricyclic Overdose

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Introduction Tricyclic Medications (sometimes called tricyclic antidepressants, or TCAs) for example;¬† amitriptyline, dosulepin, are commonly taken in overdose. They are probably one of the more dangerous medications to use in…

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Introduction These are naturally occurring chemicals found in tea, coffee, chocolate and other related foods. They are chemically similar to caffeine. They have vasodilating, bronchodilating, anti-inflammatory and immunomodulating actions, but…

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