Drug Antidote Amitriptyline Sodium Bicarbonate Beta-blockers Glucagon Benzodiazepines Flumazenil Bupivicaine Intralipid Cyanide Hydroxocobalamin / Nitrites (inhaled) Digoxin Digoxin Antibodies Heparin Protamine Hydrofluoric Acid Calcium Iron Desferrioxamine Methanol Ethanol Methaemoglobin Methyline…
Opiates Naloxone will reverse the effect of opiate overdose, typically in the presence of CNS and respiratory depression. It competitively binds opioid receptors, causing a blockade Usually given IV for…
Diuretics are commonly used medications for a variety of conditions, including hypertension, heart failure, cirrhosis and other conditions. Diuretics can affect electrolyte balance as they interfere with the control of…
Introduction Paracetamol (acetaminophen) is a widely used anti-pyrexic and analgesic, with similar efficacy in these areas to aspirin, however, unlike aspirin and NSAIDs it has virtually no anti-inflammatory properties. It…
Introduction Potassium sparing diuretics inhibit the reabsorption of sodium (and water) from the distal tubule by antagonising aldosterone. They have only a relatively weak diuretic effect. They reduce potassium excretion…
Introduction Propofol is a drug widely used for sedation and general anaesthesia. It also gained notoriety for its involvement in the death of Michael Jackson. It usually comes in a…
Proximal tubule diuretics e.g. acetazolidamide These drugs are carbonic anyhrdrase blockers. Some sodium is reabsorbed in conjunction with hydrogen. This process relies on the carbonic anhydrase to catalyse the reaction…
Quetiapine is a commonly used atypical antipsychotic medication. Indications include schizophrenia, bipolar disorder, depression, and acute delirium. Mechanism Dopamine, serotonin and adrenergic antagonist Antihistamine Binds very strongly to serotonin (5-HT)…
Legal Requirements for a prescription Hospital number or address Name of patient Date Name of drug Dose – unless only one dose available for that particular drug Signature Date of…
Mechanism of action Renin Inhibitors act by > directly inhibit renin! Renin converts angiotensinogen to angiotensin I Renin inhibitors (Aliskiren) competes with angiotensinogen for the active site of the…