Acromegaly

Acromegaly is a disorder that occurs due to an excess secretion of growth hormone (GH) Epidemiology Prevalence is approximately 40-60 million Affects M: F with a ratio of 1: 1 Mainly affects people between...

More

Addison’s Disease – Adrenal Insufficiency

Primary hypoadrenalism This term is synonymous with Addison’s disease. In this condition, there is destruction of the adrenal cortex. The presentation is notoriously varied and vague. It is potentially fatal. There will be a...

More

Adrenal Physiology

Introduction This article looks at adrenal physiology and explains the production and effects of adrenal products. For more information on mechanisms of blood pressure regulation, secretion of ions, and other effects related to the...

More

Conn’s Syndrome

Conn’s Syndrome This is basically primary hyperaldosteronism. It will cause hypernatreamia and hypokalaemia. It is a recognised cause of hypertension – but it is rare. It can also cause alkylosis (due to the exchange...

More

Cushing’s Syndrome

Glucocorticoid excess The term Cushing’s syndrome is used to describe state of excess free circulating glucocorticoid. Spontaneous forms of the syndrome are very rare – it generally occurs as a result of administered ACTH...

More

Diabetes Insipidus

Introduction Diabetes insipidus is a condition characterised by the passage of large volumes (>3L/day) of dilute urine due to impaired water resorption by the kidney, because of reduced ADH secretion from the posterior pituitary...

More

Diabetic Foot Check

In diabetes it is important to check distal circulation. Diabetes affects blood vessels, causing a loss of blood supply that can lead to ischemia and tissues damage. This is particularly the case in the...

More

Diabetic Retinopathy

This is the most common cause of blind registration for patients in the UK between 15 and 65 years.   Pathology When were they diagnosed with DM- the longer the duration the higher the...

More

Euthyroid Sick Syndrome

This condition is not very well understood! This is a condition where TSH and T3/T4 levels are low, but there is no underlying pathology of the thyroid. These test results are the same as...

More