Conn’s Syndrome

This is basically primary hyperaldosteronism. It will cause hypernatreamia and hypokalaemia.

It is a recognised cause of hypertension – but it is rare. It can also cause alkylosis (due to the exchange of sodium for hydrogen by some channels in the tubule).

It is often symptomless, but may present with symptoms of hypokalaemia – such as muscle weakness, fatigue, polyuria, cramps.

2/3 are due to a solitary mineralocorticoid producing adrenal adenoma. The other 1/3 are due to adrenal hyperplasia.

The treatment is basically laparoscopic adrenalectomy