May become endemic where standards of environmental sanitation and personal hygiene are low (ie deltas of ganges river)
vibrios multiple in small intestine producing endotoxinàstimulates cAMPàcauses secretory diarrheaàPatients rapidly lose water sodium, potassium and bicarbonateàleads to hypovolaemia, reduced CO and acidosis.
Most are asymptomatic, many have mild disease and very few have fulminant disease.
Vomiting followed by diarhoea (severe and watery white-flecked with mucous=’rice water stool’)
Dr Tom Leach MBChB DCH EMCert(ACEM) currently works as a GP Registrar and an Emergency Department CMO in Australia. He is also a Clinical Associate Lecturer at the Australian National University. After graduating from his medical degree at the University of Manchester in 2011, Tom completed his Foundation Training at Bolton Royal Hospital, before moving to Australia in 2013. He started almostadoctor whilst a third year medical student in 2009.
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