Anaemia of Chronic Disease

Introduction Anaemia of Chronic Disease (ACD) is common, particularly in the hospital setting. It occurs as a result of: Chronic infection Chronic inflammation Neoplasia Chronic kidney disease The anaemia is typically: Normochromic – the...

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Anticoagulant Therapy

Introduction Anticoagulation (“blood-thinning”) is a therapeutic mechanism used to reduce the risk of blood clots, or to treat already established blood clots for various indications, including; venous thromboembolism (for prevent and for treatment), atrial...

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Autoantibodies

Quick summary of Autoantibodies ¬† Antibody Disease Anti-dsDNA SLE Anti-mitochondrial Primary Biliary Sclerosis ASMA ‚Äď Anti- smooth muscle antibody Chronic active hepatitis pANCA Ulcerative Colitis cANCA Wegner‚Äôs granulomatosis Anti-endomysial / gliadin / transglutamase Coeliac...

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Causes of Splenomegaly

“CHICAGO” C ‚ÄstCancer H ‚ÄstHaematological malignancies ‚Äď anaemia, leukaemia, lymphoma, I ‚ÄstInfection (CMV, HEP, HIV, TB, parasitic (malaria)).¬†EBV is the most common community acquired Inflammation ‚Ästsarcoid, amyloid C ‚ÄstCongestion; portal hypertension A ‚ÄstAutoimmune(RA, SLE)...

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DVT Exam

Introduction Introduce yourself Check you have the right patient Explain what you are going to do Gain consent Wash hands!   Inspection Look around the bed for any mobility aids Look for signs of...

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Essential Thrombocythaemia

Chronic myeloproliferative disorder, persistent increase in platelet count Associated with thrombotic or haemorrhagic complications, average age 60 years Good prognosis, risk of transformation to myelofibrosis and AML Symptoms: may be asymptomatic, burning on the...

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